Dalla Lana School of Public Health

Faculty Member

Adrienne K. Chan MD, MPH, FRCPC

Research Interests

• Delivery of health services in resource limited settings:
  • Decentralization and roll-out of antiretroviral therapy and HIV related services
  • TB/HIV and NCD/HIV program integration
  • Scale up of PMTCT services
  • Task-shifting of services to address human resources for health constraints
• Clinical research: reduction of mortality due to opportunistic infections (specifically TB and cryptococcal meningitis) in HIV patient with severe immunosuppression
• Clinical characterization and evaluation of health systems effects of emerging infectious diseases (Ebola Virus Disease, COVID-19, Mpox)

Education & Training History

• Hons B. Sc. (1996; Immunology and History) and MD (2000), University of Toronto
• Internal Medicine (2004) and Adult Infectious Diseases (2006) Residency, University of Toronto
• MPH (2007; International Health), Knox Memorial Fellow, Harvard School of Public Health

Other Affiliations

• Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, University of Toronto
• Sunnybrook Health Sciences Centre and Sunnybrook Research Institute
• Institute for Health Policy, Management and Evaluation, University of Toronto

Professional Summary & Appointments

• Associate Professor, Division of Infectious Diseases, Department of Medicine, University of Toronto (Primary appointment)
• Institute for Health Policy, Management and Evaluation (Cross-appointment)
• Clinician-Investigator and Staff Physician (2014-present), Associate Medica Director Infection Prevention and Control (2020-2023), Division of Infectious Diseases, Sunnybrook Health Sciences Centre
• Medical Advisor (2011-19), Medical Coordinator (2008-10), HIV Clinic Coordinator (2007-8), Dignitas International (www.dignitasinternational.org)
• Chair, Board of Directors, Partners in Health Canada (www.pihcanada.org)

Honours & Awards

• Dean’s Humanitarian Award, Faculty of Medicine, University of Toronto, (2019)
• Inaugural Humanism in Medicine Award, Department of Medicine, University of Toronto (2018)
• Social Responsibility Award (Faculty), Postgraduate Medical Education, University of Toronto (2016)

Representative Publications

See current publications list at PubMed.

• Sundaram ME, Calzavara A, Mishra SK, Kustra R, Chan AK, Hamilton MA, Djebli M, Rosella LC, Watson T, Chen H, Chen B, Baral SD, Kwong JC.  The individual and social determinants of COVID-19 in Ontario, Canada: A population wide study.  CMAJ 2021; 193(20):E723-E734
• Molloy S, Kanyama C, Heyderman R, Loyse A, Kouanfack C, Chanda D, Mfinango A, Temfack E, Lakhi S, Lesikari S, Chan AK, Stone N, Kalata N, Karunaharan N, Gaskell K, Peirse M, Ellis J, Chawinga C, Lontsi S, Ndong JG, Bright P, Lupiya D, Chen T, Bardley J, Adams J, van der Horst C, van Oosterhout JJ, Sini V, Mapoure YN, Mwaba P, Bicanic T, Lalloo DG, Wang D, Hosseinipour MC, Lortholary O, Jaffar S, Harrison T for the ACTA Trial Study Team. Fluconazole Fluctyosine Combination and Short Course Amphotericin-based therapy for Cryptococcal Meningitis in Africa. N Engl J Med 2018; 378(11):1004-17.
• Beardsley J, Wolbers M, Kibengo FM, Kamali A, Cuc NTK, Binh TQ, Chau NVV, Farrar J, Merson L, Phuong L, Thwaites G, Kinh NV, Thuy PT, Chierakul W, Siriboon S, Thiansukhon E, Onsanit S, Supphamongkholchaikul W, Konpan P, Semran K, Chan AK, Heyderman R, Miwnjiwa E, van Oosterhout JJ, Imran D, Basri H, Mayxay M, Dance D, Phimmasone P, Rattanavong S, Lallo DG, Day JN on behalf of CryptoDex Investigators. Adjunctive steroids in HIV-associated cryptococcal meningitis: a randomized controlled trial in African and southeast Asian countries. N Engl J Med 2016; 374:542–54.
• Mattia JG, Vandy MJ, Chang JC, Platt DE, Bausch DG, Brooks T, Conteh S, Crozier I, Fowler RA, Kamara AP, Kang C, Mahadevan S, Mansaray Y, Marcell L, McKay G, O’Dempsey T, Parris V, Pinto R, Rangel A, Sala AP, Shantha J, Wolfman V, Yeh S, Chan AK, Mishra S. Early clinical sequelae of Ebola virus disease during convalescence in Sierra Leone. Lancet Infec Dis 2016; 16:331–38
• Chan AK, Mateyu G, Jahn A, Schouten E, Arora P, Mlotha W, Kambanji M, van Lettow M. Outcome assessment of decentralization of ART provision in a rural district in Malawi using an integrated primary care model. Trop Med Int Health 2010; 15s1:90-97.