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Biostatistics II

Course Number
CHL5202H
Series
5200 (Biostatistics)
Course Instructor(s)
Kevin E Thorpe, Charles (Charlie) D.G. Keown-​Stoneman

Course Description

The goal of this course is to continue development and application of skills in statistical analysis required in epidemiologic and health care research. Tutorials are an opportunity for students to ask questions and gain clarification on lecture and problem set materials.  Lab time will be used to provide students with the opportunity to gain practical experience implementing methods.

Course Objectives

  • Analysis where outcome is continuous and exposure and covariates are a mix of continuous and categorical variables (multiple linear regression)
  • Relaxing linearity assumptions of continuous exposure variables through the use of regression splines
  • Perform internal validation by means of bootstrapping or cross-validation
  • Extension to binary outcomes (multiple logistic regression)
  • Extension to time to event and censored outcomes (survival analysis)
  • Dealing with missing data
  • Introduce Bayesian methods

Methods of Assessment

Weekly quizzes 20%
Three major assignments:

  • multiple linear regression
  • logistic regression
  • survival analysis

60% (20% each)

Final exam 20%

Pre/Co-Requisite Courses